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Allele : Sox8<tm1Weg> SRY (sex determining region Y)-box 8; targeted mutation 1, Michael Wegner

Primary Identifier  MGI:2154329 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Sox8
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  In-frame insertion of a LacZ-neomycin resistance cassette replaced the complete open reading frame and both introns of the gene. RT-PCR and in situ hybridization studies indicate that expression of the LacZ marker replaced endogenous gene expression in homozygous mutant embryos and adult male mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Sox8<lacZ>,
  • Sox8<lacZ>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

27 Publication categories

Trail: Allele