Primary Identifier | MGI:2154329 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Sox8 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | In-frame insertion of a LacZ-neomycin resistance cassette replaced the complete open reading frame and both introns of the gene. RT-PCR and in situ hybridization studies indicate that expression of the LacZ marker replaced endogenous gene expression in homozygous mutant embryos and adult male mice. |