Primary Identifier | MGI:3702029 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Mbp-cre,CAG-EGFP)53Masa |
Strain of Origin | (C57BL/6N x C3H/HeN)F2 | Is Recombinase | true |
Is Wild Type | false |
description | Several transgenic lines were created (8,9,36,39,53, and 60). Lines are equivalent and line 53 was used in a subsequent publication therefore it was chosen as the representative line. |
molecularNote | The Mbp promoter region was fused to the cre gene carrying a nuclear localization signal. This transgenic insertion also carries a chicken actin promoter (CAG) promoter element and EGFP. Expression of EGFP and cre is found within the inner surface of the ear, brain, heart, lungs, liver, pancreas, spleen, kidney, intestine and skeletal muscle. |