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Protein Coding Gene : Ffar1 free fatty acid receptor 1

Primary Identifier  MGI:2684079 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  233081
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables bioactive lipid receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; ligand-gated ion channel signaling pathway; and positive regulation of transport. Acts upstream of or within insulin secretion. Located in plasma membrane. Is expressed in gut and male reproductive gland or organ. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FFAR1 (free fatty acid receptor 1).
PHENOTYPE: There are conflicting reports on the metabolic affects of disrupting this gene. Glucose metabolism lipid levels have been studied. [provided by MGI curators]
  • synonyms:
  • Ffar1,
  • G protein-coupled receptor 40,
  • Gpr40,
  • free fatty acid receptor 1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

17 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For