First Author | Cestari V | Year | 1992 |
Journal | Behav Neural Biol | Volume | 58 |
Issue | 1 | Pages | 58-63 |
PubMed ID | 1358055 | Mgi Jnum | J:2211 |
Mgi Id | MGI:50735 | Doi | 10.1016/0163-1047(92)90922-q |
Citation | Cestari V, et al. (1992) Strain-dependent effects of post-training dopamine receptor agonists and antagonists on memory storage in mice. Behav Neural Biol 58(1):58-63 |
abstractText | Post-training administration of the selective D1 or D2 agonists SKF 38393 and LY 171555 dose dependently impairs retention of an inhibitory avoidance response in DBA/2 mice. In agreement, the selective D1 or D2 antagonists SCH 23390 and (-)-sulpiride improve retention. These effects are opposite to those observed in the C57BL/6 strain, as previously reported. Moreover, B6D2F1 hybrids present a response to SKF 38393, LY 171555, SCH 23390, and (-)-sulpiride that parallels that of the C57BL/6 strain, thus suggesting that the neural mechanisms underlying the effects of DA agonists or antagonists on memory processes may be inherited through a dominant mode of inheritance. |