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Publication : Molecular evolution of the rhodopsin gene of marine lamprey, Petromyzon marinus.

First Author  Zhang H Year  1997
Journal  Gene Volume  191
Issue  1 Pages  1-6
PubMed ID  9210581 Mgi Jnum  J:41175
Mgi Id  MGI:893254 Doi  10.1016/s0378-1119(96)00864-5
Citation  Zhang H, et al. (1997) Molecular evolution of the rhodopsin gene of marine lamprey, Petromyzon marinus. Gene 191(1):1-6
abstractText  Visual pigment genes have been isolated from a marine lamprey, Petromyzon marinus. We report here the rhodopsin gene, spanning 21.2 kb from start to stop codons, making it the longest opsin gene known in vertebrates. Southern analysis suggests that the lamprey genome contains a single rhodopsin gene. The amino acid (aa) sequence deduced from this gene has 92% sequence similarity with that of the river lamprey rhodopsin. The data reveal that aa substitutions occurred more often in the transmembrane region than in the non-transmembrane region, possibly reflecting functional adaptation of the rhodopsin during the last 500 million years of the jawless fish evolution.
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