| Primary Identifier | MGI:3842434 | Allele Type | Chemically induced (ENU) |
| Gene | Krt10 | Inheritance Mode | Dominant |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false | Project Collection | Beutler Mutagenetix |
| molecularNote | This mutation was discovered by its visible phenotype in progeny of a mutagenized male mouse. Sequence analysis of all the genes in the keratin gene cluster revealed an A to T transversion at nucleotide position 547 of the keratin 10 gene, in the first of the gene's eight exons, that results in replacement of a highly conserved glutamic acid by valine at amino acid position 172 of the keratin protein (E172V), in the first linker domain. |
