Primary Identifier | MGI:6200657 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Cacna2d4 |
Strain of Origin | C57BL/6J x (C57BL/6J x SJL/J)F1/J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 2 was targeted using two sgRNAs and Cas9n (nickase version of Cas9). The result was an out-of-frame deletion (c.360_408del) that leads to a premature translation stop codon after 14 novel codons. |