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Allele : Cacna2d4<em1Leea> calcium channel, voltage-dependent, alpha 2/delta subunit 4; endonuclease-mediated mutation 1, Amy Lee

Primary Identifier  MGI:6200657 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Cacna2d4
Strain of Origin  C57BL/6J x (C57BL/6J x SJL/J)F1/J Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 2 was targeted using two sgRNAs and Cas9n (nickase version of Cas9). The result was an out-of-frame deletion (c.360_408del) that leads to a premature translation stop codon after 14 novel codons.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • alpha2delta-4 KO,
  • alpha2delta-4 KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele