Primary Identifier | MGI:2447566 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(SFTPC-RAF1)87Urr |
Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
Is Wild Type | false |
description | 11 independent transgenic lines were created. This line is a representative of the lines in which all mice develop lung adenomas and no hydronephrosis. |
molecularNote | The transgene is composed of a human SFTPC promoter, a human RAF1 cDNA, and an SV40 small T antigen intron and polyadenylation signal. 3.7 kb of human SFTPC promoter sequences was used to drive transgene expression in lung epithelium. |