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Protein Coding Gene : Mknk1 MAP kinase-interacting serine/threonine kinase 1

Primary Identifier  MGI:894316 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  17346
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ATP binding activity and protein serine/threonine kinase activity. Involved in intracellular signal transduction and response to salt stress. Acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; integumental system; liver; nervous system; and nose. Orthologous to human MKNK1 (MAPK interacting serine/threonine kinase 1).
PHENOTYPE: Homozygous null mice are viable and fertile with no gross abnormalities. [provided by MGI curators]
  • synonyms:
  • Mknk1,
  • MGI:1920925,
  • Mnk1,
  • 2410048M24Rik,
  • MAP kinase-interacting serine/threonine kinase 1,
  • RIKEN cDNA 2410048M24 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For