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Comment :

Type  MGI:General Description  in the CNS, the morphological organization of the paranodal region is often grossly disrupted, as shown by the striking eversion of glial loops often, only the paranodal loops of the innermost myelin turns remain attached to the axon, whereas the lateral loops of the outermost turns are often unattached, everted or displaced medially, indicating that the normal trapezoid organization of the myelin sheath is reversed other defects, including loops from a single myelin sheath that appose each other and myelin segments that overlap, suggest defective glial attachment