| Primary Identifier | IPR029259 | Type | PTM |
| Short Name | RICTOR_phospho |
| description | The mammalian target of rapamycin (mTOR) is a conserved Ser/Thr kinase that forms two functionally distinct complexes, mTORC1 and mTORC2, important for nutrient- and growth-factor signalling []. Rictor (rapamycin-insensitive companion of mTOR) is an essential component of the complex mTORC2 []. It appears to serve as a scaffolding protein important for maintaining mTORC2 integrity. Rictor interacts with 14-3-3 in a Thr1135-dependent manner []. Rictor can be inhibited by short-term rapamycin treatment, showing that Thr1135 is an mTORC1-regulated site [].This short region is the phoshorylation site of Rictor. |
