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Allele : Col1a1<tm2.1(CAG-cre/ERT2)Dgk> collagen, type I, alpha 1; targeted mutation 2.1, David Kirsch
Primary Identifier  MGI:5642281 Allele Type  Targeted
Attribute String  Conditional ready, Inducible, Recombinase Gene  Col1a1
Transmission  Germline Strain of Origin  129S4/SvJae
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A targeting vector was designed to insert (from 5 to 3) a CAG promoter, a frt-flanked CreERT2 (Cre recombinase fused to an estrogen receptor ligand binding domain) coding sequence, and an attB/attP-flanked neomycin (neo) resistance cassette downstream of the collagen A1 (Col1a1) promoter. PhiC31-mediated recombination removed the neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Col1a1<FRT-Cre-ER-T2-FRT>,
  • Col1a1<FRT-Cre-ER-T2-FRT>
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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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