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Publication : Expression cloning of a full-length cDNA encoding delta opioid receptor from mouse thymocytes.

First Author  Sedqi M Year  1996
Journal  J Neuroimmunol Volume  65
Issue  2 Pages  167-70
PubMed ID  8964899 Mgi Jnum  J:34425
Mgi Id  MGI:81882 Doi  10.1016/0165-5728(96)00028-8
Citation  Sedqi M, et al. (1996) Expression cloning of a full-length cDNA encoding delta opioid receptor from mouse thymocytes. J Neuroimmunol 65(2):167-70
abstractText  A delta opioid receptor complementary DNA (cDNA) was cloned by expression of cDNA library from activated thymocytes in Cos 7 cells. The deduced amino acid sequence of this receptor was similar to that described in the brain. As analyzed by southern blot hybridization, the delta opioid receptor transcripts are constitutively expressed in unactivated thymocytes. In addition, neither kappa nor mu opioid receptor transcripts were detected in thymocytes, suggesting tissue-specific opioid receptor gene expression in the immune system. The studies represent the first report of a full-length opioid receptor in the immune system.
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