Primary Identifier | MGI:3513416 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Apc |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted into intron 13 and a loxP flanked PGK-Hprt cassette into intron 14. Crossing with transgenic mice expressing Cre in the germline excised exon 14 and the Hprt cassette. RT-PCR indicated the lack of transcript in colon samples from mutants. |