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Publication : The murine Mov-34 gene: full-length cDNA and genomic organization.

First Author  Gridley T Year  1991
Journal  Genomics Volume  11
Issue  3 Pages  501-7
PubMed ID  1837787 Mgi Jnum  J:11579
Mgi Id  MGI:59990 Doi  10.1016/0888-7543(91)90056-k
Citation  Gridley T, et al. (1991) The murine Mov-34 gene: full-length cDNA and genomic organization. Genomics 11(3):501-7
abstractText  The Mov-34 mutation is a recessive embryonic lethal mutation caused by experimental introduction of a recombinant Moloney murine leukemia provirus into the mouse germline. We have cloned a full-length cDNA from the Mov-34 gene, the transcription unit disrupted by the proviral integration. This cDNA is predicted to encode a novel 321-amino acid, 36-kDa protein of unknown function. Overlapping phage lambda clones containing the entire Mov-34 gene have been isolated. The Mov-34 gene spans just over 8 kb and contains seven exons. The 5' flanking region of the Mov-34 gene contains neither TATA nor CAAT box sequences, and 5' end mapping by primer extension and ribonuclease protection reveal multiple transcription initiation sites.
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