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Allele : Unc80<em1Dren> unc-80, NALCN activator; endonuclease-mediated mutation 1, Dejian Ren

Primary Identifier  MGI:6451179 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Unc80
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology deleted exon 3 and part of the surrounding introns (total of 157 nucleotides) leading to truncation after V47. This truncation removes 3279 of 3326 residues of the protein. Western blot analysis with an antibody against the C-terminal 15 residues confirmed absence of protein in the brain.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Unc80<->,
  • Unc80<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories