Primary Identifier | MGI:5804692 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Il2 |
Transmission | Germline | Strain of Origin | C57BL/6 |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A targeting vector was designed to insert a cre recombinase cDNA, an frt-flanked neo cassette, and an internal ribosome entry site (IRES) into the Il2 gene just upstream of the first codon. The mice with correct targeted inserts were bred with Actin-FLPe females (on a C57BL/6 congenic background) to remove the neo selection cassette. |