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Protein Coding Gene : Jmjd6 jumonji domain containing 6

Primary Identifier  MGI:1858910 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  107817
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables RNA binding activity; identical protein binding activity; and signaling receptor activity. Involved in several processes, including negative regulation of protein homooligomerization; regulation of mRNA splicing, via spliceosome; and sprouting angiogenesis. Acts upstream of or within several processes, including circulatory system development; hemopoiesis; and recognition of apoptotic cell. Located in cytosol; nuclear lumen; and plasma membrane. Part of ribonucleoprotein complex. Is expressed in several structures, including central nervous system; early conceptus; gonad; hemolymphoid system gland; and tooth. Orthologous to human JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase).
PHENOTYPE: Mice homozygous for disruptions in this gene show perinatal lethality. Abnormalities are observed in the nervous. respiratory, cardiovascular, digestive, renal, hematopoietic, and immune systems. [provided by MGI curators]
  • synonyms:
  • D11Ertd195e,
  • RIKEN cDNA 5730436I23 gene,
  • DNA segment, Chr 11, ERATO Doi 195, expressed,
  • phosphatidylserine receptor-pending,
  • PtdSerR,
  • PSR,
  • MGI:1261867,
  • Ptdsr,
  • MGI:1917797,
  • 5730436I23Rik,
  • jumonji domain containing 6,
  • mKIAA0585,
  • Jmjd6,
  • phosphatidylserine receptor

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For