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Protein Coding Gene : Arhgap1 Rho GTPase activating protein 1

Primary Identifier  MGI:2445003 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  228359
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables GTPase activator activity. Predicted to be involved in several processes, including negative regulation of endocytic recycling; small GTPase-mediated signal transduction; and transferrin transport. Located in plasma membrane and ruffle. Is expressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human ARHGAP1 (Rho GTPase activating protein 1).
PHENOTYPE: Homozygous null mice display incomplete penetrance of postnatal lethality, increased apoptosis, and growth retardation. [provided by MGI curators]
  • synonyms:
  • expressed sequence C76222,
  • p50rhoGAP,
  • MGI:2139453,
  • B230365D05Rik,
  • Cdc42GAP,
  • RIKEN cDNA B230365D05 gene,
  • C76222,
  • Rho GTPase activating protein 1,
  • Arhgap1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

5 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

17 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For