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Protein Coding Gene : Plxnb1 plexin B1

Primary Identifier  MGI:2154238 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  235611
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables GTPase activating protein binding activity and semaphorin receptor activity. Involved in several processes, including negative regulation of osteoblast proliferation; nervous system development; and positive regulation of intracellular signal transduction. Acts upstream of or within positive regulation of axonogenesis. Part of semaphorin receptor complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human PLXNB1 (plexin B1).
PHENOTYPE: Homozygous null mutants are viable and fertile and show no apparent defects in development, adult histology or basic functional parameters. However, a transitory renal phenotype, characterized by increased ureteric branching and enlarged kidneys, is noted over early stages of renal development. [provided by MGI curators]
  • synonyms:
  • plexin B1,
  • MGI:2143234,
  • RIKEN cDNA 2900002G15 gene,
  • Plxnb1,
  • 2900002G15Rik,
  • mKIAA0407,
  • expressed sequence AU042020,
  • MGI:1917470,
  • AU042020

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

15 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For