Primary Identifier | MGI:2446217 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 230936 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable chromatin binding activity; chromatin-protein adaptor activity; and methylated histone binding activity. Predicted to be involved in mitotic chromosome condensation and regulation of DNA repair. Predicted to act upstream of or within cell division; chromatin organization; and chromosome condensation. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; early conceptus; ganglia; genitourinary system; and sensory organ. Orthologous to human PHF13 (PHD finger protein 13). PHENOTYPE: Mice homozygous for a gene trap allele exhibit reduced male fertility over time associated with impaired spermatogonial stem cell differentiation and male germ cell apoptosis. [provided by MGI curators] |