| Primary Identifier | MGI:1922637 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 75387 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables NAD+ ADP-ribosyltransferase activity; NAD-dependent protein deacetylase activity; and lipoamidase activity. Involved in several processes, including carboxylic acid metabolic process; positive regulation of lipid biosynthetic process; and regulation of cellular ketone metabolic process. Acts upstream of or within negative regulation of insulin secretion. Located in mitochondrial inner membrane and mitochondrial matrix. Is expressed in several structures, including aorta; brain; gonad; respiratory system; and thyroid gland. Orthologous to human SIRT4 (sirtuin 4). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile and display no apparent phenotypic abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
