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Publication : Expression of basic-helix-loop-helix transcription factor ME2 during brain development and in the regions of neuronal plasticity in the adult brain.

First Author  Soosaar A Year  1994
Journal  Brain Res Mol Brain Res Volume  25
Issue  1-2 Pages  176-80
PubMed ID  7984047 Mgi Jnum  J:20051
Mgi Id  MGI:68164 Doi  10.1016/0169-328x(94)90297-6
Citation  Soosaar A, et al. (1994) Expression of basic-helix-loop-helix transcription factor ME2 during brain development and in the regions of neuronal plasticity in the adult brain. Brain Res Mol Brain Res 25(1-2):176-80
abstractText  We report the isolation of a cDNA encoding the mouse class A bHLH transcription factor ME2 and the analysis of its expression. ME2 is expressed in the cerebral cortex, Purkinje and granule cell layers of the cerebellum, olfactory neuroepithelium, pyramidal cells of hippocampal layers CA1-CA4, and in the granular cells of the dentate gyrus. The specific expression of ME2 during development and in the regions of neuronal plasticity in the adult brain suggest that ME2 may have a regulatory function in developmental processes as well as during neuronal plasticity.
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