|  Help  |  About  |  Contact Us

Protein Coding Gene : Tpp2 tripeptidyl peptidase II

Primary Identifier  MGI:102724 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  22019
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable exopeptidase activity; identical protein binding activity; and peptide binding activity. Predicted to be involved in intracellular amino acid homeostasis and protein catabolic process. Predicted to act upstream of or within proteolysis. Predicted to be located in nuclear body. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human TPP2 (tripeptidyl peptidase 2).
PHENOTYPE: Engineered mutations of this gene result in decreased lifespan and symptoms of immunohematopoietic senescence. [provided by MGI curators]
  • synonyms:
  • tripeptidyl peptidase II,
  • Tpp2,
  • TppII,
  • MGD-MRK-19628

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For