Primary Identifier | IPR042056 | Type | Domain |
Short Name | MIB1/2_ZZ |
description | This entry represents the Zinc finger found in the mammalian MIB1/2 protein and Drosophila Mind bomb (D-mib) protein. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. MIB1 and MIB2 are E3 ubiquitin-protein ligases []. Mind bomb is an E3 ubiqitin ligase that has been shown to regulate signaling by the Notch ligand Delta in Drosophila melanogaster [, , , ]. |