| Primary Identifier | MGI:1916078 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 68828 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Acts upstream of or within intermediate filament-based process. Located in several cellular components, including Z disc; neuromuscular junction; and sarcolemma. Is expressed in tibialis anterior. Orthologous to human SYNC (syncoilin, intermediate filament protein). PHENOTYPE: Homozygotes for one knock-out allele show reduced generation of isometric stress in skeletal muscle but a normal response to eccentric contraction-induced injury. Homozygotes for another knock-out allele show impaired contractility and increased skeletalmuscle damage under a forced exercise regime. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
