| Primary Identifier | MGI:6155013 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Sort1 |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 14 and a FRT-flanked neomycin selection cassette and a second loxP site were inserted downstream of exon 14. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 14 which encodes for part of the beta-propeller domain. Western blot analysis confirmed absence of protein in the liver of homozygotes. |
