| Primary Identifier | MGI:3045302 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 442827 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable GTP binding activity and GTPase activity. Acts upstream of or within histamine secretion by mast cell and histamine secretion mediated by IgE immunoglobulin. Predicted to be located in plasma membrane. Orthologous to human RAB44 (RAB44, member RAS oncogene family). PHENOTYPE: Mice homozygous for a null allele of both isoforms exhibit impaired granule exocytosis in mast cells and IgE-mediated anaphylaxis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
