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Protein Domain : FYVE and coiled-coil domain-containing protein 1

Primary Identifier  IPR042654 Type  Family
Short Name  FYCO1
description  FYVE and coiled-coil domain-containing protein 1 (FYCO1) is a transport adaptor that binds to phosphatidylinositol 3-phosphate, to Rab7, and to LC3 to mediate transport of late endosomes and autophagosomes along microtubules in the plus end direction [, ]. FYCO1 contains a 9-amino acid-long F-type LIR (LC3-interacting region) motif, which is essential to facilitate efficient maturation of autophagosomes under basal conditions [].

0 Child Features

0 Parent Features

4 Protein Domain Regions