| First Author | Truett GE | Year | 1996 |
| Journal | Mamm Genome | Volume | 7 |
| Issue | 5 | Pages | 356-8 |
| PubMed ID | 8661723 | Mgi Jnum | J:33357 |
| Mgi Id | MGI:80838 | Doi | 10.1007/s003359900103 |
| Citation | Truett GE, et al. (1996) A rat homolog of the mouse deafness mutant jerker (je). Mamm Genome 7(5):356-8 |
| abstractText | An autosomal recessive deafness mutant was discovered in our colony of Zucker (ZUC) rats. These mutants behave like shaker-waltzer deafness mutants, and their inner ear pathology classifies them among neuroepithelial degeneration type of deafness mutants. To determine whether this rat deafness mutation (-) defines a unique locus or one that has been previously described, we mapped its chromosomal location. F2 progeny of (Pbrc:ZUC x BN/Crl) A/a B/b H/h +/- F1 rats were scored for coat color and behavioral phenotypes. Segregation analysis indicated that the deafness locus might be loosely linked with B on rat Chromosome (Chr) 5 (RNO5). Therefore, 40 -/- rats were scored for BN and ZUC alleles at four additional loci, D5Mit11, D5Mit13, Oprd1, and Gnb1, known to map to RNO5 or its homolog, mouse Chr 4 (MMU4). Linkage analysis established the gene order (cM distance) |
