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Comment :

Type  MGI:General Description  transgenic T cells from mice on a NOD background have lower levels of T cell receptor expressed transgenic T cells from mice on a NOD background have a severe reduction in response to its cognate antigen (RNAse peptide) presented by Ak than do transgenic T cells from a C57BL/6 background hybridomas created from these T cells respond normally to antigen suggesting a cell intrinsic anergy