| Primary Identifier | MGI:95942 | Organism | mouse, laboratory |
| Chromosome | 17 | Mgi Type | polymorphic pseudogene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including beta-2-microglobulin binding activity; peptide antigen binding activity; and signaling receptor binding activity. Acts upstream of or within inner ear development. Predicted to be located in several cellular components, including Golgi apparatus; cell surface; and endoplasmic reticulum. Predicted to be part of MHC class I protein complex and MHC class Ib protein complex. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; lung; and musculoskeletal system. Human ortholog(s) of this gene implicated in several diseases, including Stevens-Johnson syndrome; asthma (multiple); autoimmune disease (multiple); eye disease (multiple); and inner ear disease (multiple). Orthologous to human HLA-B (major histocompatibility complex, class I, B); HLA-C (major histocompatibility complex, class I, C); and HLA-E (major histocompatibility complex, class I, E). |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
