Primary Identifier | MGI:2180196 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 246316 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Involved in inhibitory synapse assembly. Located in extracellular space. Is expressed in alimentary system; central nervous system; nose; orbito-sphenoid; and salivary gland primordium. Orthologous to human LGI2 (leucine rich repeat LGI family member 2). PHENOTYPE: Mice homozygous develop normally with normal lifespans and fertility. Lgi2 and Lgi3 exhibit postnatal growth retardation, tremors, absent Kv1 channels, and postnatal lethality. [provided by MGI curators] |