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Allele : Cyp17a1<tm1Mell> cytochrome P450, family 17, subfamily a, polypeptide 1; targeted mutation 1, Synthia H Mellon

Primary Identifier  MGI:3047328 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cyp17a1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Part of exon 5 and all of exon 6 were replaced with a neo. Exon 6 contains the Ozols peptide, which comprises amino acids 346 to 366 and contains amino acids crucial for redox partner binding. Immunostaining of embryos revealed absence of protein in homozygous mutants.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • P450c17<->,
  • P450c17<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele