| Primary Identifier | MGI:1336997 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 14768 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables glutathione transferase activity. Involved in cellular detoxification. Predicted to be located in cytoplasm and membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human LANCL1 (LanC like glutathione S-transferase 1). PHENOTYPE: Mice homozygous for a null mutation exhibit postnatal neurodegeneration with increased oxidative stress and mitochondrial impairment, and reduced male fertility associated with testicular atrophy, asthenospermia, oligospermia, increased male germ cell apoptosis, and spermatozoal oxidative damage. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
