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Protein Coding Gene : Kpna7 karyopherin subunit alpha 7

Primary Identifier  MGI:2141165 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  381686
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Acts upstream of or within blastocyst development and regulation of gene expression. Located in female germ cell nucleus and spindle. Is expressed in early conceptus; gonad; and liver. Orthologous to human KPNA7 (karyopherin subunit alpha 7).
PHENOTYPE: Mice homozygous or heterozygous for a null mutation display smaller litter sizes with preferential loss of females and accelerated cell cycles post fertilization resulting in loss of embryos. [provided by MGI curators]
  • synonyms:
  • gene model 1055, (NCBI),
  • Gm1055,
  • LOC381686,
  • karyopherin subunit alpha 7,
  • expressed sequence AW146299,
  • MGI:2685901,
  • Kpna7,
  • importin alpha 2,
  • AW146299

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

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0 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For