|  Help  |  About  |  Contact Us

Allele : Retnlb<em1Lvh> resistin like beta; endonuclease-mediated mutation 1, Lora Hooper

Primary Identifier  MGI:6105937 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Retnlb
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Embryos were injected with guide RNA targeting exon 2 and Cas9 nuclease. Sequencing of several mice revealed an animal carrying the deletion of a single adenine nucleotide in this signal peptide coding region (CGTCTCCCTTCTCCCACTGATA -> CGTCTCCCTTCTCCCACTG*TA) which created a frameshift and premature stop codon.
  • mutations:
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele