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Allele : Tln1<em1Mgin> talin 1; endonuclease-mediated mutation 1, Mark H Ginsberg
Primary Identifier  MGI:7260105 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Tln1
Strain of Origin  (C57BL/6J x SJL)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  Using CRISPR/Cas9 technology, nucleotides in exon 1 were substituted to result in the amino acid substitutions of Arg 35 to Glu (R35E). Arg 35 forms crucial salt bridges with an acidic patch on Rap1b.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Tln1<R35E>,
  • Tln1<R35E>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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