Primary Identifier | MGI:7260105 | Allele Type | Endonuclease-mediated |
Attribute String | Not Specified | Gene | Tln1 |
Strain of Origin | (C57BL/6J x SJL)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Using CRISPR/Cas9 technology, nucleotides in exon 1 were substituted to result in the amino acid substitutions of Arg 35 to Glu (R35E). Arg 35 forms crucial salt bridges with an acidic patch on Rap1b. |