Primary Identifier | MGI:3849082 | Allele Type | Chemically induced (ENU) |
Gene | Six1 | Inheritance Mode | Dominant |
Strain of Origin | C3HeB/FeJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | ENU mutagenesis induced an A to G transition at position 411 resulting in an amino acid substitution of glycine for glutamic acid at position 135 (E135G). This mutation in the homeobox is predicted to cause destabilisation of DNA binding. |