Primary Identifier | IPR032700 | Type | Family |
Short Name | IZUMO1 |
description | Izumo sperm-egg fusion protein 1 (IZUMO1) is an essential sperm cell-surface protein required for fertilisation by acting as a ligand for IZUMO1R/JUNO receptor on eggs []. It is a member of an immunoglobulin superfamily and possesses a well-conserved putative N-glycosylation site. However, glycosylation is not essential for the function of IZUMO, but has a role in protecting it from fragmentation in cauda epididymis []. |