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Protein Coding Gene : Hgfac hepatocyte growth factor activator

Primary Identifier  MGI:1859281 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  54426
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in blood coagulation and zymogen activation. Located in rough endoplasmic reticulum. Is expressed in brain; liver; liver left lobe; liver right lobe; and metanephros. Orthologous to human HGFAC (HGF activator).
PHENOTYPE: Homozygous null mice display impaired intestinal regeneration and increased mortality after intestinal injury. [provided by MGI curators]
  • synonyms:
  • HGFA,
  • Hgfac,
  • hepatocyte growth factor activator

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

8 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For