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Protein Coding Gene : H2-DMb1 histocompatibility 2, class II, locus Mb1
Primary Identifier  MGI:95922 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  14999
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable MHC class II protein complex binding activity and peptide antigen binding activity. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and chaperone cofactor-dependent protein refolding. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of MHC class II protein complex. Predicted to be active in late endosome membrane and lysosomal membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human HLA-DMB (major histocompatibility complex, class II, DM beta).
  • synonyms:
  • expressed sequence AI385589,
  • histocompatibility 2, class II, locus Mb1,
  • H-2Mb1,
  • H2-Mb1,
  • MGI:2146833,
  • MGD-MRK-10406,
  • H2-DMb1,
  • AI385589,
  • H2-M beta1,
  • MGD-MRK-10518
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Canonical gene --> Transcripts in specific strains.

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3 Pathways

Trail: ProteinCodingGene

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