| First Author | Hara T | Year | 1993 |
| Journal | Somat Cell Mol Genet | Volume | 19 |
| Issue | 6 | Pages | 571-5 |
| PubMed ID | 8128316 | Mgi Jnum | J:17295 |
| Mgi Id | MGI:65343 | Doi | 10.1007/BF01233383 |
| Citation | Hara T, et al. (1993) The UDP-galactose translocator gene is mapped to band Xp11.23-p11.22 containing the Wiskott-Aldrich syndrome locus. Somat Cell Mol Genet 19(6):571-5 |
| abstractText | We have cloned a segment of the human gene encoding UDP-galactose translocator by genetic complementation of its defective mutant in mouse FM3A cells. Chromosome mapping using fluorescent in situ hybridization revealed that the cloned gene hybridized to the Xp11.23-11.23 region of the X chromosome. This region is shared by the locus of Wiskott-Aldrich syndrome, an X-linked recessive immunodeficiency disorder, characterized by defective sugar chains on cell surface components. Genetic and phenotypic similarities suggest a possible link between UDP-galactose translocator and the Wiskott-Aldrich syndrome (WAS). |
