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Allele : Igf1sl4<C57BL/6J> IGF-1 serum levels 4; C57BL/6J
Primary Identifier  MGI:3046887 Allele Type  QTL
Gene  Igf1sl4 Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
description  Igf1sl1 and Igf1sl4 exhibit epistatic interaction. Homozygosity for C3H/HeJ-derived alleles at Igf1sl4 negates the IGF-1 lowering effect of Igf1sl1. When Igf1sl4 is homozygous or heterozygous for C57BL/6J-derived alleles the effect of Igfsl1 can be observed.
molecularNote  This allele confers decreased serum IGF-1 levels and decreased BMD in conjunction with C3H/HeJ-derived alleles at Igf1sl1.
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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