|  Help  |  About  |  Contact Us

Protein Coding Gene : Cga glycoprotein hormones, alpha subunit

Primary Identifier  MGI:88390 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  12640
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable follicle-stimulating hormone activity. Acts upstream of or within several processes, including gonadotropin secretion; thyroid gland development; and thyroid hormone generation. Predicted to be located in extracellular region. Predicted to be part of follicle-stimulating hormone complex. Predicted to be active in extracellular space. Is expressed in brain; future pituitary; and retina nuclear layer. Orthologous to human CGA (glycoprotein hormones, alpha polypeptide).
PHENOTYPE: Homozygous null mutants exhibit male and female sterility with hypogonadism, dwarfism, hypothyroidism, and both hypertrophy and hyperplasia of pituitary thyrotropes. [provided by MGI curators]
  • synonyms:
  • alpha-GSU,
  • aGSU,
  • GPHalpha,
  • MGD-MRK-1964,
  • thyrotropin stimulating hormone, alpha subunit,
  • alphaSU,
  • glycoprotein hormones, alpha subunit,
  • Tsha,
  • Cga,
  • alphaGSU,
  • MGD-MRK-15273

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

30 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

4 Driver For