| Primary Identifier | IPR017219 | Type | Family |
| Short Name | Peptidoglycan_deacetylase |
| description | This entry represents peptidoglycan GlcNAc deacetylases, including Peptidoglycan-N-acetylglucosamine deacetylase (PgdA) from Streptococcus pneumoniae, which confers host lysozyme resistance and contributes to pneumococcal virulence [, ]. Structural analysis from S. pneumoniae revealed that PGDA is a metalloenzyme using a His-His-Asp zinc-binding triad with a nearby aspartic acid and histidine acting as the catalytic base and acid, respectively []. This entry also includes Peptidoglycan-N-acetylmuramic acid deacetylase PdaC from Bacillus subtilis, which has high amino acid sequence similarity with Streptococcus pneumoniae PgdA []. |
