| Primary Identifier | MGI:1917566 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 70316 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable acyl binding activity; acyl carrier activity; and mitochondrial large ribosomal subunit binding activity. Predicted to be involved in [2Fe-2S] cluster assembly and mitochondrial respiratory chain complex I assembly. Predicted to act upstream of or within fatty acid biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human NDUFAB1 (NADH:ubiquinone oxidoreductase subunit AB1). PHENOTYPE: Skeletal muscle-specific knock-out leads to smaller body size, hypoglycemia, hypoinsulinemia, reduced muscle and liver glycogen levels, disrupted mitochondrial cristae and premature death within five days after birth. Overexpression increases glucose metabolism and protects against diet-induced obesity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
