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Protein Domain : Sorting nexin-5

Primary Identifier  IPR028654 Type  Family
Short Name  SNX5
description  Sorting nexin-5 (SNX5) belongs to the sorting nexin family, which contains a conserved PX (phox homology) domain that is responsible for binding to specific phosphoinositides []. SNX5 also contains a BAR domain that is C terminus to the PX domain. Besides being involved in several stages of intracellular trafficking, SNX5 also plays a role in macropinocytosis and in the internalisation of EGFR after EGF stimulation [, ].

0 Child Features

1 Parent Features

4 Protein Domain Regions