| Primary Identifier | MGI:1341813 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 110751 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and integumental system. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and rhinitis. Orthologous to human ADAM33 (ADAM metallopeptidase domain 33). PHENOTYPE: Mice homozygous for a targeted gene deletion are viable, fertile, developmentally normal and display normal allergen-induced airway hyperreactivity, IgE production, mucus metaplasia, and airway inflammation in an OVA-induced model of allergic asthma. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
