| Primary Identifier | MGI:1889342 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 54390 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable kinase binding activity. Predicted to be involved in regulation of T cell activation. Predicted to act upstream of or within adaptive immune response. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human SIT1 (signaling threshold regulating transmembrane adaptor 1). PHENOTYPE: Homozygous null mice exhibit altered T-cell development, thymus hyperplasia, decreased lymph node cellularity and are more susceptible to develop experimental autoimmune encephalomyelitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
